Adoptive transfer of CX3CR1 transduced-T regulatory cells improves homing to the atherosclerotic plaques and dampens atherosclerosis progression

نویسندگان

چکیده

Background and Aims: Patients with FH showed impaired immunosuppressive response associated increased inflammation. We tested Adoptive Cell Therapy (ACT) Treg engineered to selectively migrate in the atherosclerotic plaque dampen immune-inflammatory arterial wall.

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ژورنال

عنوان ژورنال: Atherosclerosis

سال: 2021

ISSN: ['0021-9150', '1879-1484']

DOI: https://doi.org/10.1016/j.atherosclerosis.2021.06.096